-Probiotic use reduces risk of acute infectious diarrhea, nosocomial diarrhea, antibiotic-associated diarrhea, traveler’s diarrhea, and Clostridium difficile-associated diarrhea in pediatric patients.

-Probiotic use reduces the risk of antibiotic-associated diarrhea and Clostridium difficile-associated diarrhea in adult patients.


-Probiotic use improves defecation frequency, pain with defecation and abdominal pain in pediatric patients with functional chronic intestinal constipation.

-Probiotic use increases the number of weekly bowel movement in adult patients with chronic idiopathic constipation.

Inflammatory Bowel Disease

-Probiotic use increases remission rates of ulcerative colitis in adult patients.

-Probiotics prevents relapse of Crohn’s disease and recurrence of pouchitis.

-Irritable bowel syndrome (IBS)

-Probiotic use improves global symptoms, bloating, and flatulence in both pediatric and adult patients of irritable bowel syndrome.

H. Pylori

-Probiotic use as an adjunct to antibiotics increases the rate of H. pylori eradication.

-Heptic encephalopathy

-Probiotic use is effective in reducing the development of overt hepatic encephalopathy among adult patients with cirrhosis.